Since release 2.6, python's SSL support is based on OpenSSL. Prior to 2.6, it was based on a more-limited implementation.
It appears that this earlier implementation may fail to connect when the underlying socket is configured as non blocking, or configured with a timeout.
This causes some of the qpid tools to fail to connect when used with SSL. For example, qpid-config.
Also, the use of the older version of SSL's client-authentication appears to be broken.